123264330962ENSG00000186198ENSMUSG00000053862Q86UW2Q80WK2NM_178859NM_178933NP_849190NP_849264Organic solute transporter beta, also known as OST-beta, is a protein which in humans is encoded by the OSTB gene.

[5][6] OST-beta together with OST-alpha is able to transport estrone sulfate, taurocholate, digoxin, and prostaglandin E2 across cell membranes.

[6][7] The Ost-alpha / Ost-beta heterodimer, but not the individual subunits, stimulates sodium-independent bile acid uptake.

[7] The heterodimer furthermore is essential for intestinal bile acid transport.

[8] OST-alpha and OST-beta have high expression in the testis, colon, liver, small intestine, kidney, ovary, and adrenal gland.