The hospital was designed by Parkin Architects and Adamson Associates and built by a joint venture of EllisDon and Carillion.

On Sundays, half hourly throughout the day, though buses usually start late in the morning; a bit before 8 am.

[11][12] The future planned Dundas BRT will run directly south of the Oakville Trafalgar Memorial Hospital on Dundas Street, a planned bus rapid transit line from Kipling Terminal in Etobicoke, Toronto, connecting to other services; TTC Line 2 (subway), GO Transit Milton Line (regional rail), and GO Transit, MiWay, and TTC buses.

[17] Neyagawa Boulevard is planned to be extended to Milton adding extra access to the hospital.

William Halton Parkway is also being extended from Neyagawa Boulevard to Third Line, therefore adding even more access to the hospital.