Occupation of Coxim was a Paraguayan military operation led by Colonel Francisco Isidoro Resquín that resulted in the capture of the village of Coxim, now Mato Grosso do Sul, during the Paraguayan War.

Colonel Resquín detached 300 soldiers and some cannons from Miranda, the base camp for the invaders, and headed for the village.

The column advanced on horseback and encountered great difficulties in the 120 kilometers of almost impassable terrain.

Coxim's defense was in charge of only seven Brazilian soldiers under the command of retired captain Antônio Pedro dos Santos.

It was said that the Paraguayans were marching to the capital with 8,000 soldiers and a large number of cannons and horses, which never occurred.