[1][2] It is endemic to southeastern Brazil and known from Minas Gerais, Goiás, and São Paulo states.

The male advertisement call is composed of a single, multi-pulsed note.

[3] Odontophrynus cultripes is a fossorial species that occurs in open areas, forest edges, and suburban gardens.

It is an abundant species that breeds explosively in temporary pools, including man-made ones.

Although not threatened, habitat loss caused by infrastructure development and agricultural activities can negatively impact the species.