The series is centered on the lives of two twentysomething friends, British stud Euan Pierce and play-it-safe American Mike Platt, after they move into the posh Hadley Building on New York's Centre Street.

Rounding out the cast are Mike's girlfriend, Liz Lombardi, their wacky friend, Vietnamese restaurant owner Chau Presley, and secretly sensitive gangsta rapper Status Quo.

Among the show's notable guest stars are Carmen Electra (as herself), and American Pie alumni Eugene Levy (as urologist Dr. Barry Wasserman), Jason Biggs (as Rick Steve, the man with two first names) and Shannon Elizabeth (as Dawn, a girlfriend of Chau's who adores seeing him get beat up).

The show has one-off appearances by Jenna Fischer in "The Backup" and Zachary Quinto in "Diddler on the Roof" before they found fame on The Office and Heroes, respectively.

There is also One Tree Hill star Bethany Joy Galeotti, and Perrey Reeves in "A Cute Triangle" prior to her turn on Entourage.