The Officer Creek, part of the Lake Eyre basin, is an ephemeral watercourse located in the Far North region in the Australian state of South Australia.

The creek rises in the Musgrave Ranges and flows through the Aboriginal community of Kaltjiti in the Anangu Pitjantjatjara Yankunytjatjara Lands.

Officer Creek is usually a dry sandy bed and only flows at times of very high rainfall.

In September 1873 during his second trip into the South Australian interior, Ernest Giles and another party member, William Tietkens, encountered 200 male Aborigines.

[2] Officer Creek took its name from the surname of one of the donors towards Giles' expedition that he wished to honour in that way.