SR 135 travels from its southern terminus at a T-intersection with U.S. Route 50 (US 50) approximately two miles (3.2 km) south of the village of Lynchburg to its northern terminus in Lynchburg at a T-intersection with SR 134.

Beginning at a T-intersection with US 50 in Dodson Township, SR 135 travels to the northwest through a landscape primarily composed of farmland, with a few homes appearing along the way.

The highway then turns west onto South Street at a four-way stop intersection, and continues through the heavily residential portion of the village through its endpoint where it meets SR 134 at a T-intersection.

It has maintained the same short alignment in western Highland County throughout its history.

[2][3] Pop Culture Reference: This route is mentioned in an episode of Seinfeld ("The Bottle Deposit, Part II") where Kramer and Newman are following Jerry's stolen Saab convertible through Ohio on their way to Michigan in a mail truck full of bottles to recycle.