The southern terminus of State Route 206 is at a T-intersection with State Route 541 approximately 6.50 miles (10.46 km) east of the unincorporated community of Bladensburg.

Its northern terminus is 3.50 miles (5.63 km) east of the village of Brinkhaven at its junction with U.S. Route 62.

State Route 206 passes through the northwestern quadrant of Coshocton County and enters into the southwestern corner of Holmes County.

There are no segments of State Route 206 that are included within the National Highway System.

[7][8] Then, in 1937, State Route 206 took on its current shape as it was extended northerly to its current northern terminus at U.S. Route 62 east of Brinkhaven.