State Route 344 (SR 344) is an east-west state highway lying entirely in Columbiana County, Ohio.

Its western terminus is at State Route 14 and State Route 9 in downtown Salem, and its eastern terminus is along a concurrency with State Route 164 in downtown Columbiana.

In that same year, the highway was rerouted between former SR 558 and Leetonia along a previously unnumbered road.

[4][5] No significant changes have taken place to this state route since 1981.

[5][6] The entire route is in Columbiana County.