Its northern terminus is at SR 2 at an intersection just outside Camp Perry about three and a half miles (5.6 km) west of Port Clinton.

Throughout its history, the primary purpose of SR 358 has been to provide state highway access to Camp Perry.

SR 358 exists entirely within Erie Township in the central portion of Ottawa County.

It begins at a T-intersection with SR 163 east of Oak Harbor, opposite the Port Clinton Golf Course, which is situated on the north banks of the Portage River.

The highway crosses over the Norfolk Southern Railway, and passes by a mix of woods and fields on the short journey up to its endpoint at SR 2, along a multi-lane stretch of the major state route opposite of the main entrance into Camp Perry.