The highway runs from its southern terminus at a signalized intersection with U.S. Route 224 (US 224) on the Summit–Portage county line approximately 0.75 miles (1.21 km) south of Mogadore on the border of Springfield Township and Suffield Township to its northern terminus at a diamond interchange with Interstate 76 (I-76), at its exit 29 within the Tallmadge city limits.

The portion of SR 532 that was removed from the state highway system continues from I-76 to the center of Tallmadge as Southeast Avenue.

This state highway is not included as a component of the National Highway System, a system of routes identified as being most important for the economy, mobility and defense of the country.

SR 532 then utilized its entire present alignment, continuing northwest of where the I-76 interchange is located today along Southeast Avenue up to the downtown Tallmadge traffic circle.

Consequently, at that point the state highway took on the status of short connector route between US 224 and I-76 that it has today.