SR 55 meets South Market Street, the former routing of US 25, and turns northeasterly toward the central business district.

[2] Departing from the traffic circle in a northeasterly fashion, SR 55 intersects Water Street, then immediately crosses the Great Miami River.

After crossing the river, SR 55 turns easterly onto Staunton Road from Market Street.

Entering into Staunton Township, SR 55 starts to trend northeasterly, with the residential setting yielding to a more rural landscape featuring vast amounts of farmland, with the occasional house situated off of the highway.

Turning northeasterly again, SR 55 passes occasional patches of trees amidst the vast farmland.

East of there, SR 55 resumes an easterly path, intersecting Alcony-Conover Road, and crossing into Champaign County.

[3] Into Champaign County, SR 55 makes a brief trip through Jackson Township en route to Christiansburg.

SR 55 passes through the hamlet of Thackery, briefly turning north at the Hampton-Donnellsville Road intersection there before resuming its easterly course.

[3] Proceeding eastward, SR 55 meets Bair Road, then turns northeasterly upon crossing over the Mad River.

SR 55 then parallels the Mad River for a stretch, intersecting Hickory Grove Road in the process.

Jeffrey L. Rice Memorial Highway",[7] in honor of a Troy High School and Upper Valley Career Center graduate who was killed in Kandahar, Afghanistan, while serving in the Army, on July 19, 2012.

[13] In 1926, SR 55 was extended on the western end along a previously unnumbered road to Ludlow Falls.

In that same year, however, the advent of the U.S. Highway System resulted in a major truncation of SR 55 on the east side.