Through this stretch, the two-lane highway encounters a blend of farmland, occasional homes and even a few businesses.

[2] Continuing northwest of SR 61, the setting that SR 601 passes through remains unchanged up through the intersection from which Perrin Road heads northeasterly, and Old State Road goes southward.

Passing through that intersection, SR 601 encounters one subdivision on each side of the roadway, then promptly crosses into Erie County, and correspondingly, the village of Milan.

Through Milan, SR 601 is routed along Main Street, and passes through a primarily residential portion of the community.

[3][4] Media related to Ohio State Route 601 at Wikimedia Commons