For its entire length, SR 716 runs parallel to, and approximately four miles (6.4 km) to the east of, U.S. Route 127.

The highway heads northward through downtown Osgood and then into the rural regions, which includes spontaneous residential homes and fields.

The highway crosses the line into Mercer County and continues northward through rural areas.

[3] The highway remains mainly unchanged for a little while until it nears the Marion Township village of Maria Stein.

The route continues northward for a short distance into Chickasaw, where it terminates at SR 274.