Leaving Rarden, the route increases in elevation to Mount Joy, the highest point in Scioto County.

After weaving between Scioto and Pike County for about four miles (6.4 km), the route joins the Appalachian Highway, SR 32 and subsequently SR 124.

Following these concurrences, SR 772 continues its journey north through scenic terrain and small communities until it reaches its northern terminus at the US 50 and SR 104 concurrence in Chillicothe.

[2] The first part of SR 772 brought into the state highway system was the section between SR 124 in Idaho and US 23 just south of its current northern terminus in Chillicothe in 1937.

[3][4] By 1939, the route had been extended south to its current southern terminus in Rarden.