Olga Duque de Ospina (née Duque Palma; July 14, 1930 - September 19, 2019) was a Colombian lawyer and politician, a member of the Conservative party, having served as a member of the Chamber of Representatives representing Bogotá, D.C. from 1970 to 1974.

She later served as Governor of Huila and later served as Senator of Colombia from 1978 to 1982 and again from 1986 to 1990.

She would finally serve as Minister of National Education, being the sixth woman in the history of Colombia to hold that position.

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