[1] About this time, she was summoned to the palace as companion and instructor of the younger but equally gifted Anna d'Este, daughter of Renata, duchess of Ferrara.

[1] Many people with literary fame or Protestant leanings, like John Calvin, Vittoria Colonna and Clément Marot visited the court of the duchess.

When she returned to court, Anna d'Este's marriage to Francis, Duke of Guise left Olympia isolated.

They finally succeeded in reaching Heidelberg in 1554 where a medical lectureship had been obtained for Grundler through the influence of the Erbach family, by whom they had been hospitably entertained during their flight.

[1] In 1558 (or 1556, sources differ), after her death, Opera omnia, a major collection of some of her Greek letters and Latin dialogues, was published in Basel,[4] a labour which she entrusted to her friend and correspondent Caelius Secundus Curio.