The Ombrone (Latin: Umbro) is a 160-kilometre (99 mi) long river in Tuscany, central Italy.

The Ombrone's source is at San Gusmè, near Castelnuovo Berardenga, on the south-eastern side of the Monti del Chianti.

After a twisting route, it receives the waters of the tributaries Arbia, Merse and Orcia before reaching the plain near Istia d'Ombrone.

[1] It subsequently passes near the city of Grosseto, before flowing into the Tyrrhenian Sea.

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