On a New Organic Base in the Coca Leaves is an 1860 dissertation written by Albert Niemann.
[1] Its title in German is Über eine neue organische Base in den Cocablättern.
The piece describes, in detail, how Niemann isolated cocaine, a crystalline alkaloid.
He wrote of the alkaloid's "colourless transparent prisms" and said that, "Its solutions have an alkaline reaction, a bitter taste, promote the flow of saliva and leave a peculiar numbness, followed by a sense of cold when applied to the tongue."
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