[5] This species is found along the western coast of the Pacific from the Bahia de Los Angeles in the Gulf of California to Ecuador.

They cannot be on the lower levels because they do not have strong enough grips to withstand the rising and falling tides and the harsh wave activity that occurs in the rocky intertidal zone.

[4] O. binneyi feeding and general activity patterns have strong correlations with the rise and fall of the tides.

[4] Onchidal, when isolated from the defensive secretion of the Onchidella binneyi, has demonstrated growth inhibition of Staphylococcus aureus.

O. binneyi performs naturally cytotoxic activities that have a significant effect on lymphocytic leukemia cell growth in humans.