One Little Pill is a documentary film about the use of generic medications (primarily naltrexone, but also nalmefene) for treating and curing alcoholism.

It was produced by Zard Productions as a film project for the C Three Foundation and released on Vimeo and VHX for on-demand viewing in October 2014.

This certainly makes a welcome change, to celebrities going on about the 12-step solution.The film describes the application of opioid blockers (naltrexone or nalmefene) as an alternative to help alcohol addicts in place of other more mainstream solutions such as twelve-step programs.

In 2013/4 the Scottish Medicines Consortium (SMC) approved nalmefene for use as part of the NHS National Services Scotland.

[6][7] The treatment is described in the film as follows: a single dosage of naltrexone is taken one hour before drinking alcohol, but not on other occasions.