The fourth season of the American mystery comedy-drama television series Only Murders in the Building, often abbreviated as OMITB, premiered on August 27, 2024, on Hulu.

Paul Rudd and Meryl Streep return from the previous season as special guest stars, along with Zach Galifianakis, Eugene Levy, and Eva Longoria as fictionalized versions of themselves.

The trio confronts the Brothers sisters, who admit that they were in Dudenoff's apartment on the night of Sazz's murder, but only to visit him and to place hidden cameras in the building for behind-the-scenes footage of the film.

[7][8] In April 2024, Desmin Borges, Siena Werber, Lilian Rebelo, Richard Kind, Daphne Rubin-Vega, Catherine Cohen, and Jin Ha joined the cast in recurring capacities.

[11] The episodes in the season were written by John Hoffman, Joshua Allen Griffith, Kristin Newman, Ben Smith, Pete Swanson, Madeleine George, J. J. Philbin, Ella Robinson Brooks, Rick Wiener, Kenny Schwartz, Matteo Borghese, Rob Turbovsky, Jake Schnesel, and Alex Bigelow.

The website's critics consensus states, "The gang is back together in a more metatextual season full of famous faces, continuing Only Murders in the Building's reign as one of television's most delightful comedies.