The route winds north, crossing the railway line before ending at Highway 66, part of the Trans-Canada Highway, between Swastika and Chaput Hughes, southwest of the primary urban area of Kirkland Lake.

The route is 19.8 kilometres (12.3 mi) long, and is situated entirely within Timiskaming District.

The 240-kilometre (150 mi) Ferguson Highway, mostly gravelled, was built north from New Liskeard to Cochrane via Earlton, Englehart, Dane, Swastika, Matheson, Monteith and Porquis Junction beginning in late 1923; it was complete by 1925.

[5] During the early 1950s, the Round Lake Diversion was constructed, bypassing the original route of Highway 11 from south of Tarzwell to the present day junction with Highway 66.

[4] The following table lists the major junctions along Highway 112, as noted by the Ministry of Transportation of Ontario.