Oosterwijzend is a hamlet in the municipality of Drechterland, in the Dutch province of North-Holland.

Oosterwijzend lays just to the east of where the canal the Wijzend used to bend southwards from Binnenwijzend.

Nowadays, Oosterwijzend and Westerwijzend are being separated by a paved road beginning in Hoogkarspel.

Oosterwijzend is the smaller hamlet of the two, and is formally considered a part of Hoogkarspel.

The northern part is untilled, and borders the Zaandam-Enkhuizen railway.