Opercularia echinocephala (bristly headed stinkweed) is a species of plant within the genus Opercularia, in the family Rubiaceae.

It is endemic to the southwest of Western Australia.

[3] O. echinocephala is a spreading perennial from 0.1 to 1.3 m high which grows on flat plains and river banks on sands and lateritic soils.

[4] It is found in the IBRA regions of Esperance Plains, Jarrah Forest, Swan Coastal Plain and Warren.

[1][2] No synonyms are listed by APNI,[1] nor by Plants of the World online.