Ophiem is an unincorporated community in Lynn Township, Henry County, Illinois, United States.

[2] It was founded in 1850 by Johannes and Carl Johan Samuelson, who named it "Opphem", after their family farm in Sweden.

A post office was established in 1871.

[3] Ophiem first appeared as a census designated place in the 2020 U.S.

This Henry County, Illinois location article is a stub.