[2][3] Eisenberg hosted the weekly NPR and WNYC trivia, puzzle, and game show Ask Me Another,[4] with the "one-man house band" Jonathan Coulton.

[1][9] She frequently hosts and tours with The Moth,[1] a storytelling show, and is featured on one of their Audience Favorites CDs.

[14] She has also been featured in a number of anthology books, including: I Killed: True Stories of the Road from America's Top Comics alongside Dennis Miller, Joan Rivers, Chris Rock, and Jerry Seinfeld;[15] Rejected: Tales of the Failed, Dumped, and Canceled;[16] and Heeb Magazine's Sex, Drugs and Gefilte Fish (2010).

She was also in the original Toronto Fringe production of The Drowsy Chaperone in 1999,[18] which later became a Tony Award-winning Broadway show.

[citation needed] Eisenberg lives in an apartment in Brooklyn, New York City, with her husband, Jonathan Baylis (a writer-producer-editor and comic creator of So Buttons Comix) and their son Lucas.