It is paraphyletic with Ophraella artemisiae which it differs little from genetically despite being dissimilar morphologically, this is a result of peripatric speciation.

Both the holotype and the allotype of naked flea beetle were collected in 1955 near the locality of Comrey, next to the Milk River Valley.

[3] Other specimens come from Hilda, Medicine Hat, Onefour, and Waterton.

Ophraella nuda is a yellow-brown coloured flea beetle with four vertical lines on its elytra and three brown spots on its pronotum.

The elytra however does actually have short, fine, transparent hair which is only visible at higher magnifications.