The mall is adjacent to the Grand Ole Opry House and the Gaylord Opryland Resort & Convention Center.

The anchor stores are Regal Cinemas, Madame Tussauds, Sun & Ski Sports, Off Broadway Shoe Warehouse, Bass Pro Shops, Ralph Lauren, Nike Outlet, H&M, Old Navy, Forever 21, and Dave & Buster's.

Friday's, Burger King, Villa Fresh Italian Kitchen, Johnny Rockets, The Cheesecake Factory, Rainforest Cafe, Dave & Buster's, Saltgrass Steakhouse, Aquarium Restaurant, Bavarian Bierhaus, Chuy's Mexican Food and Romano's Macaroni Grill restaurants are located inside and outside the food court.

The current site of Opry Mills was originally Opryland Themepark, a popular theme park which operated from 1972 to 1997.

[5] Opry Mills temporarily closed in May 2010 after the water from the 2010 Tennessee floods reached as high as 10 feet inside the mall.