"[2] As an abolitionist, Orange Scott stated that "If slavery be a moral evil, the conclusion is irresistible that it ought to be immediately abandoned.

[1] Following his personal conversion to Christ at the age of 20, Orange Scott began serving as a circuit rider for the Methodist Episcopal Church.

[1] In 1834, he published an abolitionist treatise, arguing that the institution of slavery was a moral evil and should be wholly rejected by the Church.

The Methodists in all parts of the United States have braved, and, finally, to a considerable extent, changed public opinion.

"He who has made of one blood, all nations of men to dwell on the earth' [Acts 17:26] must look with disapprobation upon such a system of complicated wrongs, as American slavery... abolition is from above (of which I have no more doubt than of the truth of Christianity)..." Along with three others, Orange Scott published in 1843 in the True Wesleyan (a periodical founded by him and Jotham Horton), an announcement to hold A Wesleyan Anti-Slavery Convention at the Methodist church in Andover, Massachusetts with the purpose of planning the formation of a separate denomination "free from Episcopacy and Slavery".

[1] Orange Scott was elected to preside over the Utica Convention, which would organize the Wesleyan Methodist Church.