OrderUp started as an online food ordering business, called LionMenus, which served State College, PA.[1] In 2009, the founders relocated to Baltimore, MD and formed LocalUp to expand to additional markets.

[1] OrderUp is one of the first companies to provide a digital franchise in order to target local markets.

[6] In August 2014, the company announced a $7 million Series A investment round focused on growing its technical team and expanding its delivery service nationally.

[9][10] In October 2018, Grubhub acquired certain assets of 11 remaining franchisee-owned OrderUp food delivery markets across California, Colorado, Indiana, Missouri, Oregon, Oklahoma, and Virginia.

[11] As of August 2013, OrderUp had sites in about 25 American cities and had launched a mobile application from which users can order food using Android or iOS devices.