OR 212 begins at Interstate 205 and OR 213 in Clackamas and heads east as a four lane highway.

Along the way, there are numerous intersections with backroads that lead to Gresham, Portland's biggest eastern suburb.

It then enters the town of Boring, remaining as a two lane road and reaches its eastern terminus at an interchange with US 26, northwest of Sandy.

A previous alignment through Boring ran due west onto Fireman Way, curving south onto 272nd.

Milepoints are as reported by ODOT and do not necessarily reflect current mileage.