It is located 46 kilometres (29 mi) north of Chișinău, in the vicinity of Orhei.

The park is located in Codri, the forested area in the hilly part of central Moldova.

[2] The main tourist attractions of the Orhei National Park are the Trebujeni landscape reserve, the main part of the Curchi tract (Mănăstirea Curchi), the Țigănești landscape reserve, a number of ancient archaeological sites, the city of the Golden Horde Shehr al-Jedid, a Moldovan medieval city with a fortress, 5 monasteries (including Old Orhei, Curchi, Țigănești), 4 noble estates, other interesting objects.

[3] Localities within the park include Ghetlova, Morozeni, Neculăieuca, Ivancea, Persecina, Donici, Teleșeu, Pohorniceni, Puțintei, Trebujeni, Seliște, Vatici, Codreanca, Romănești, Țigănești, Bravicea, Săseni, and Mașcăuți.

[4] Cultural and natural reserve Old Orhei (Romanian: Orheiul Vechi) is a candidate for inclusion to the list of UNESCO World Heritage Sites since 2017.