In 1977, Orange Memorial and Holiday hospitals consolidated to form the new Orlando Regional Medical Center, in 1984 the Air Care Team was formed providing scene and interfacility air transport to the Central Florida area, and in 1985 Sand Lake Hospital was built.

The Arnold Palmer Hospital for Children & Women opened in 1989 and in 1991 M. D. Anderson Cancer Center Orlando was created.

In 1992, ORMC changed its corporate name to Orlando Regional Healthcare System to reflect the growing network of facilities.

[10]{} Orlando Health serves 1.6 million Central Florida residents and several thousand international patients annually.

Orlando Health is considered a disproportionate share hospital, meaning it receives special funding because it treats significant populations of indigent patients.

[13] Their sponsorship was a carry-over partnership that was established when Orlando City SC was part of the United Soccer League Pro Division.