The Circolo Hospital and Macchi Foundation (Italian: Ospedale di Circolo e Fondazione Macchi) is the largest hospital of Varese, Italy.

The Hospital has existed for 800 years: the first settlement dates back to the hospital in 1173 in the hills of Bosto for work of a religious community dedicated to helping the poor and mentally ill.

Since '800, Varese became a place of meetings and studies by eminent scientists and clinicians: Sacco, Bizzozero, Riva Rocci and Golgi.

In 1929 the hospital settled in its present location: the park of the villa of the tenor Francesco Tamagno.

Moreover, it is home of the Department of Clinical and Experimental Medicine - DMCS of the University of Insubria.