Osteocephalus cannatellai is a frog in the family Hylidae endemic to Ecuador and Colombia.

The ventrum is gray or cream in color with lighter spots.

The iris of the eye is bronze in color with dark reticulations.

Some frogs have bright blue pigmentation near the groin and on the legs.

It has been observed to perch on leaves and branches 0.5 to 2.3 meters above the forest floor.