[2] Prior to 2008, Partskhaladze worked at the Ministry of Internal Affairs in various responsible positions, in addition to being a member of the Temporary Energy Commission of the Parliament of Georgia.

[3] On 7 November 2013, Georgian Prime Minister Irakli Garibashvili appointed Partskhaladze as Prosecutor General.

[2] In November 2018 he was charged with beating the former head of the State Audit Office, Lasha Tordia, in May 2017, and granted 5,000 GEL bail.

From September 2022, he was recorded in the Russian Federation Unified State Register of Entrepreneurs and owned shares in Russian-based company.

According to the U.S. State Department, Partskhaladze "worked with the Russian Federal Security Service to influence Georgian politics and society to benefit Russia".