The Otay Mesa East Port of Entry is a planned border crossing between San Diego and Tijuana, approximately two miles east of the existing Otay Mesa Port of Entry.

The crossing will connect the Otay Centenario borough of Tijuana with East Otay Mesa in unincorporated San Diego County, an as-yet undeveloped area slotted for future development including a business park.

[1] Although the crossing will allow cars and pedestrians, it is mainly designed for trucks and commercial vehicles.

In July 2014, Mexican Undersecretary of Infrastructure of the Secretariat of Communications and Transportation Raúl Murrieta Cummings and the Secretary of the California Department of Transportation (Caltrans), Brian P. Kelly, signed a memorandum of understanding to build and put the new port of entry into operation.

[2][3][4][5] Construction began at the initial ground breaking in August 2022, after long delays.