He was regarded as a pioneer in the twin methodology of genetics research and in the study of the inheritance of diseases and anomalies.

[1] A Nazi-affiliated eugenicist with an interest in racial hygiene, he was an advocate of compulsory sterilization programs in the first half of the 20th century.

He also maintained a close friendship with his relative, Adam von Trott zu Solz, a leading resistance figure.

Anthropological investigations on the most diverse racial groups of this concentration camp are being carried out with permission of the SS Reichsführer [Himmler]; the blood samples are being sent to my laboratory for analysis.Verschuer wrote in the report that the war conditions had made it difficult for the KWI-A to procure "twin materials" for study, and that Mengele's unique position at Auschwitz offered a special opportunity in this respect.

In the summer of 1944, Mengele and his Jewish slave assistant Dr. Miklós Nyiszli sent other "scientific materials" to the KWI-A, including the bodies of murdered Roma, internal organs of dead children, skeletons of two murdered Jews, and blood samples of twins infected by Mengele with typhus.

However, the commission in charge of rebuilding the Kaiser Wilhelm Gesellschaft decreed that "Verschuer should be considered not as a collaborator, but one of the most dangerous Nazi activists of the Third Reich."

Many of his wartime students were similarly appointed to top positions in universities of Erlangen, Frankfurt, Düsseldorf, and Münster.

In his denazification hearing, Verschuer was deemed to be a Nazi fellow traveler (Mitläufer, a relatively mild categorization meaning someone who was neither a supporter or member of the regime nor an active opponent), and fined 600 ℛ︁ℳ︁.

Leo Alexander who investigated the case concluded that no solid evidence could be found, and considered it likely that Verschuer had destroyed any possibly incriminating material.

Deeply religious, he also concerned himself with questions of Christian ethics, and argued that eugenics must be based on human dignity and love for mankind; according to historian Sheila F. Weiss he "turned his back on" Nazi beliefs.