[citation needed] Březina was born in the small town of Počátky, Pelhřimov District, and took his inspiration from the mysterious landscape of the Českomoravská Vrchovina region, straddling Bohemia and Moravia, where he spent his whole life.

Around 1895 he pondered questions regarding the meaning of life, and wrote his first book of poems Tajemné dálky, expressing his separation from the outer world and his seeking solace in the arts.

In his second book, Svítání na západě (1896), Březina explored pain as a means of cognition, and held death to be the key to understanding the mystery of life.

[1]), and culminates in his last book of poems, Ruce (1901), in a vision of a magical chain formed by all hands, building up the external world.

His books of essays constitute the integral part of his work, and his extensive correspondence serves as a commentary on his creative activities and philosophy.