After time as a private tutor in France and England, Wilhelm Wildermuth then moved to be a professor of modern languages in the Lyzeum (now the Gymnasium) in Tübingen.

From the very beginning the young couple were friends with Ludwig Uhland and his wife, the poet Karl Mayer's family, Klüpfl-Schwab and later several university professors.

Her stories met a public taste and she was printed in the widely read family periodicals such as Daheim and Die Gartenlaube, which made her known to other contemporary writers.

In 1870, she founded the children's magazine Jugendgarten, later continued by her daughters Agnes Willms and Adelheid Wildermuth.

In her fiftieth year her health was strongly attacked by a nervous disorder, and in July 1877, aged 60, she died of a stroke.