Our Lady of the Sacred Heart College is a Roman Catholic high school for girls located in the Adelaide suburb of Enfield, South Australia, Australia.

The College was founded in 1947 by the Daughters of Our Lady of the Sacred Heart, members of a religious congregation founded by Father Jules Chevalier in France in 1874.

It contains nine new classrooms, a laboratory, a home economics centre, a common room, a staff room and a canteen.

The college has two sister schools of the same name, also founded by the Daughters of Our Lady of the Sacred Heart, one in Melbourne and the other in Sydney.

Each year exchange programs are run between the schools.