Ovarian tissue cryopreservation

Tissue can then be thawed and implanted near the fallopian, either orthotopic (on the natural location) or heterotopic (on the abdominal wall),[2] where it starts to produce new eggs, allowing normal conception to take place.

[6] Women with malignant diseases that undergo treatment utilizing irradiation or gonadotoxic drugs, have an increase probability of losing ovarian function resulting in infertility.

In 2004 Jacques Donnez in Belgium reported the first successful birth from frozen tissue using a protocol developed in Roger Gosden’s laboratory, where Oktay had studied.

[9] However, Sherman Silber in St. Louis, Missouri, and another of Gosden’s collaborators, Dror Meirow at the Sheba Medical Center in Israel, and subsequently others have proven beyond doubt the technique is effective.

The first birth following transplantation of ovarian tissue stored at a central cryo bank and transported overnight has been achieved by centers of the Fertiprotekt network in Germany 2011.