In addition to the immediate Overton vicinity, the campus also serves rural areas in eastern Smith County.

The Theatre department has a long string of State UIL One Act Play appearances, with a 20-year streak of district championships led by longtime Drama instructor Lillian Cohagen, who retired in 1980.

[4] In 1997 OHS won a state Class 1A One Act Play championship with Confederate Letters, written and directed by Barre Gonzalez The Overton Mustangs compete in these sports - The Mustang football team competes in Coach Chester Roy Stadium,[6] named in honor of the first African-American member of the faculty following desegregation.

Overton's football program is notable for having won at least one district championship in every single decade starting in the 1930s, including a string of state playoff appearances from the 1980s through the 1990s, with the most recent league title coming in 2005.

The Mustang baseball team has continued this success into the 2009–2010 season, beginning the year ranked #1 in the state in Class 1A en route to a 30–3 regular season record, a first district championship, and a second consecutive appearance in the state semifinals.