[10] Studies on the limited amount of cases on ovotesticular syndrome shows the condition does not cause cognitive impairment.

Individuals with these conditions in the Late Middle Ages were considered monsters, that is, prodigies warning of divine judgment.

• Only 3 reports exist attributing specific cases of the condition to some form of duplication of the SOX9 gene; making this an incredibly rare cause.

Due to the genetic makeup of an SRY gene, it implies that ovotesticular syndrome is more of a heterogeneous condition.

[21] Encountered karyotypes include 46XX/46XY, or 46XX/47XXY or XX & XY with SRY mutations, mixed chromosomal anomalies or hormone deficiency/excess disorders, 47XXY.

[28][30] In 1994, a study on 283 cases found 21 pregnancies from 10 individuals with ovotesticular syndrome, while one allegedly fathered a child.

[33] If a human chimera is formed from a male and female zygote fusing into a single embryo, giving an individual functional gonadal tissue of both types, such self-fertilization is feasible.

[27][23] Having ovotesticular syndrome of sexual development can make one inadmissible for service in the United States Armed Forces.

v. Aaronson, advanced by intersex civil society organization interACT with the Southern Poverty Law Center, was brought before the courts in 2013.

[37][38][39][40] The child in the case was born in December 2004 with ovotestes, initially determined as male, but subsequently assigned female and placed in the care of South Carolina Department of Social Services in February 2005.

The defendant in the case, Dr. Ian Aaronson, had written in 2001 that "feminizing genitoplasty on an infant who might eventually identify herself as a boy would be catastrophic".

In January 2015, the Court of Appeals for the Fourth Circuit reversed this decision and dismissed the complaint, stating that, it did not "mean to diminish the severe harm that M.C.