The National Center for Biotechnology Information does not indicate that any phylogenetic analysis has been published on any Owilfordia species that would confirm its position as a unique genus in the family Plagiorhynchidae.

O. schmidti was found in hosts (small Indian mongoose) living in Lucknow, India.

[3] The life cycle of an acanthocephalan consists of three stages beginning when an infective acanthor (development of an egg) is released from the intestines of the definitive host and then ingested by an arthropod, the intermediate host.

This stage involves penetrating the wall of the mesenteron or the intestine of the intermediate host and growing.

There are no reported cases of Owilfordia infesting humans in the English language medical literature.