The Printery, characterized by its brown shingled exterior, served as the operational base for the Oyster Bay Guardian, a weekly newspaper established by Nelson Disbrow in 1899.

In 1905, interactions with a competing newspaper figure named Kennehan resulted in the Disbrows' lease being revoked from the Vail Building.

In 1967, the Disbrow family sold the newspaper to the newly formed Oyster Bay Publishing Company, a consortium of local women who elected Edwina Snow to the position of managing partner.

The Disbrow family independently sold the Printery building to Elizabeth Schneider, who began her own endeavor as a private printer.

The Guardian newspaper had also been located at 32 East Main Street, the former home of the grandparents of its Editor Emeritus Gloria O'Rourke who wrote a column called “Harbor Lights”.