P2 receptor may refer to: Nucleotides, if released into the extracellular environment, can lead to cell death or other harmful cellular consequences.
To avoid cellular damage, nucleotides should be neutralized, which is accomplished by P2 receptors.
P2X receptors are ATP activated channels that allow the passage of ions across cell membranes.
Extracellular ATP and the related purine and pyrimidine nucleotides exert their functions via signalling through membrane-bound purinergic P2 receptors.
These receptors are widely expressed throughout the body on various immune and nonimmune cells.