1UAP511818542ENSG00000106333ENSMUSG00000029718Q15113Q61398NM_002593NM_008788NP_002584NP_032814Procollagen C-endopeptidase enhancer 1 is an enzyme that in humans is encoded by the PCOLCE gene.

[5][6][7] Fibrillar collagen types I-III are synthesized as precursor molecules known as procollagens.

These precursors contain amino- and carboxyl-terminal peptide extensions known as N- and C-propeptides, respectively, which are cleaved, upon secretion of procollagen from the cell, to yield the mature triple helical, highly structured fibrils.

This gene encodes a glycoprotein which binds and drives the enzymatic cleavage of type I procollagen and heightens activity.

[7] This article on a gene on human chromosome 7 is a stub.