As the perfluorinated derivative of butyric acid, this colourless liquid is prepared by electrofluorination of the corresponding butyryl fluoride.

Esters derived from PFBA readily undergo condensation, owing to their electrophilicity.

Specialized ligands for metal ions are generated capitalizing on this property, such as Eufod.

Other effects of PFBA exposure included delayed development and decreased red blood cells and hemoglobin.

[4] The Minnesota Department of Health (MDH) developed a guidance value of 7 ppb (μg/L) for PFBA in drinking water.